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KMID : 0352519850220010335
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Korea Univercity Medical Journal
1985 Volume.22 No. 1 p.335 ~ p.341
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A Study of Serum Immunoglobulins in the Toxemic Pregnant Women and Their Neonates
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薛弘烈/Seol, Hong Ryul
金善行/洪性鳳/Kim, Sun Haing/Hong, Sung Bong
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Abstract
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It has ions been considered that toxemia of pregnancy might be an immunologic process, and this study was designed to explore possible abnormalities in the immunologic process in toxemic pregnant women.
IgG, IgA and IgM were measured by radial immunodiffusion plate technique in maternal and umbilical cord sera of toxemic patients and in normal pregnant cases at the time of delivery.
The values obtained in the toxemic patients were compared with those from the normal term pregnant women, and the following results were obtained.
1. The level of IgG in maternal sera of toxemic group were significantly decreased than that of the normal pregnant group. (p<0.05)
2. The levels of IgA and.IgM in maternal sera demonstrated no significant difference between normal pregnant and toxemic patients.
3. Though the levels of IgG and IgA in cord sera of toxemic patient were slightly lower than those of the normal pregnant group, the difference was not statistically significant.
4. The level of IgM in cord sera of toxemic group was markedly lower than that of normal pregnant group and the difference was statistically significant. (p<0.05)
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KEYWORD
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